Building a Team That Improves Itself: Lean at the Wellcome Sanger Spatial Genomics Team

Continuous improvement in a scientific research team starts with helping people see their own work differently. The Spatial Genomics team at Wellcome Sanger Institute were a relatively new team using cutting-edge techniques. With a scale-up deadline approaching and all delivery under strict Covid restrictions, they needed to analyse and improve their processes quickly.

The Challenge

The team needed to operate at a significantly higher scale from early 2021 but their processes had never been systematically mapped or improved. Lab layout was complex. Sample tracking was consuming significant time. And all of this needed to be resolved through remote delivery.

What We Did

WBT designed and delivered a series of half-day collaborative workshops, blending Lean learning with live improvement activity. The team were helped to understand their processes in their entirety including the people, process, and technology.

Key outputs included a redesigned lab layout using optimal flow principles, a visual management board for real-time sample tracking, smaller batch size experiments, and Statistical Process Control (SPC) measures developed by the team themselves.

The Results

  • New lab designed using optimal flow methods and implemented
  • Visual management board introducedcontinuous improvement scientific research team with every sample tracked in real time
  • Research scientist customers receiving data back faster with significantly fewer queries
  • Team fully self-sufficient in continuous improvement, owning and driving their own change agenda

“By learning to see our process through a Lean lens we were able to identify the waste steps, which primarily revolved around wasting significant amounts of time tracking samples.”

Minal Patel, Senior Scientific Manager, Wellcome Sanger Institute

“Spatial is no longer something I stress about. I know they are doing the critical thinking and improvements for themselves and they are just on top of things now.”

Rachel Nelson, Senior Scientific Manager, Wellcome Sanger Institute

Could your organisation benefit from a similar approach?
Book a free 30-minute diagnostic call with Lee Walker. Call 07736 379911 or email info@wbt.orWalker Business Transformation helped the Wellcome Sanger Spatial Genomics team prepare to operate at scale, redesign their lab, and build the confidence and tools to drive continuous improvement themselves.g.uk

From 28 Days to 9: Eliminating a Backlog in the Wellcome Sanger Genotyping Lab

Lean Six Sigma laboratory improvement delivered dramatic results at the Wellcome Sanger Genotyping Lab. Following a period of staff turnover, the team was in difficulty. A backlog of 160 plates had built up. Processing times had stretched to 28 days. Clients were chasing work daily and some had already begun outsourcing to third-party suppliers.

The Challenge

Newer team members lacked the skills to handle the full range of work. Experienced staff were cherry-picking easier plates, leaving the hardest work untouched. The team had no shared understanding of their own performance.

What We Did

WBT applied a Systems Thinking approach, helping the team see how their work actually flowed, not how they assumed it did.

  • Introduced 5S, all work organised in date order, eliminating cherry picking
  • Developed team-owned performance measures using Statistical Process Control (SPC)
  • Introduced daily huddles around a shared work board
  • Built skills transfer into daily workflow with experienced staff coaching newer members on harder plates in real time

The Results

  • Processing time reduced from 28 days to under 9 days
  • Backlog reduced from 160 to 23 plates
  • Approximately 30 daily client chase requests eliminated entirely

The team moved from working as individuals to operating as one unit with shared accountability and daily improvement routines embedded into how they worked.

Could your organisation benefit from a similar approach?
Book a free 30-minute diagnostic call with Lee Walker. Call 07736 379911 or email info@wbt.org.uk